Smartcard communication protocols follow well-established standards (connector size and location, voltages, signals, logical transport protocol...) so chances are that card readers are indeed interchangeable.
What is a Schlage card?
Sold in quantities of 50 to work with the Schlage Control Lock. ... Schlage® multi-technology credentials combine 125 kHz proximity and 13.56 MHz smart technologies in one contactless card, simplifying access control solutions and offering flexibility for users.