Can Zofran cause severe constipation?

Can Zofran cause severe constipation?

Zofran (ondansetron) is used to relieve nausea and vomiting commonly associated with cancer treatments like chemotherapy and radiation. It can also be used to prevent and treat post-surgical nausea and vomiting. Common side effects associated with Zofran include headache, drowsiness, constipation and the chills.

How do you treat constipation due to medication?

- Laxatives work in two ways: - Stimulant laxatives help stool move along your bowel or. - Just as you need to eat every day, you must take laxatives every day for them to work. - The first laxative you should try is the stimulant type called sennosides.

Can I take a stool softener with Zofran?

No interactions were found between Colace and Zofran. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

How can I relieve constipation quickly?

- Take a fiber supplement. - Eat a serving of high-fiber food. - Drink a glass of water. - Take a laxative stimulant. - Take an osmotic. - Try a lubricant laxative. - Use a stool softener. - Try an enema.

Why was Zofran taken off the market?

WASHINGTON -- The 32-mg dose of the anti-nausea drug ondansetron (Zofran) has been pulled from the market because of concerns about cardiac problems, the FDA announced Tuesday. Ondansetron is approved for preventing chemotherapy-induced nausea and vomiting, and, in lower doses, for postoperative nausea and vomiting.4 Dec 2012

What are side effects of Zofran?

Headache, lightheadedness, dizziness, drowsiness, tiredness, or constipation may occur. If these effects persist or worsen, notify your doctor promptly. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects.

How long do side effects of Zofran last?

How long do side effects last? Most common Zofran side effects such as headache, drowsiness, constipation, and diarrhea go away when the drug is discontinued. Zofran has a half-life of three to four hours in healthy adults, but this may be increased to six to eight hours in older adults.15 Sept 2021

What are common side effects adverse reactions of ondansetron?

- headache. - constipation. - weakness. - tiredness. - chills. - drowsiness.

Why was Zofran discontinued?

FDA Drug Safety Communications & Zofran Recall In 2012, the 32 mg intravenous dose of Zofran was pulled from the market due to concerns that it could trigger QT interval prolongation, a heart rhythm disorder that could lead to an abnormal and potentially fatal heart rhythm called Torsades de Pointes.

Was Zofran discontinued?

The Food and Drug Administration (FDA) has posted a discontinuation notice for Zofran Oral Solution (ondansetron; Novartis).17 Nov 2016

Is Zofran high risk?

However, now some people suggest otherwise. One recent meta-analysis of eight studies suggested that exposure to ondansetron in the first trimester could cause a very small increase in the risk of heart defects and orofacial malformations like cleft palate in babies.30 Sept 2020

What is the Zofran lawsuit about?

Families of children who suffered birth defects after mothers took Zofran while pregnant have sued GlaxoSmithKline over allegations that it marketed the drug to pregnant women without FDA approval and failed to warn about risks.

Can I take Zofran on empty stomach?

Ondansetron can be taken with or without food. The first dose of ondansetron is usually taken before the start of your surgery, chemotherapy, or radiation treatment. Follow your doctor's dosing instructions very carefully. Take the ondansetron regular tablet with a full glass of water.16 Nov 2020

What if I throw up after taking Zofran?

If you vomit within one hour taking your first Zofran Tablet of each course prescribed to you, you should take the same dose again. If you continue to vomit, tell your doctor.

Will Zofran upset your stomach?

Many people using this medication do not have serious side effects. Tell your doctor immediately if any of these unlikely but serious side effects occur: stomach pain, muscle spasm/stiffness, vision changes (e.g., temporary loss of vision, blurred vision).