In a double-blind, clinical trial, both Zoloft and Prozac improved depression based on different scores for depression and anxiety as well as sleep. While both SSRIs were found to be effective, Zoloft was found to have lower severity of side effects.Jan 7, 2020
Should I switch from Zoloft to Prozac?
If you've been diagnosed with depression, it's common and normal to try different antidepressants before finding an effective treatment for your symptoms. If Zoloft isn't an effective medication for you, your healthcare provider may recommend switching to Prozac.Dec 9, 2020
Which causes more weight gain Prozac or Zoloft?
That being said, one study published in 2016 in the Journal of Clinical Medicine found that Zoloft can lead to an overall greater weight gain than Prozac when taken long-term. The study found that people taking Prozac for two years gained an average of 4.6 pounds.Aug 17, 2021
What is better than Zoloft for anxiety?
A 2014 study published in International Clinical Psychopharmacology suggested that Lexapro may be more effective and better tolerated than Zoloft or Paxil. Lexapro has different binding site interactions which may lead to better efficacy and tolerability.Dec 2, 2019
Does Zoloft cause weight gain than Prozac?
Antipsychotic drugs, antidepressants , and mood stabilizers are common drugs that have the most potential to increase weight gain. All 12 of the leading antidepressants, including fluoxetine (Prozac), sertraline (Zoloft), and escitalopram (Lexapro), make gaining weight more likely.
Which antidepressants cause the most weight gain?
The antidepressants most likely to cause weight gain include amitriptyline (Brand name: Elavil), mirtazapine (Remeron), paroxetine (Paxil, Brisdelle, Pexeva), escitalopram (Lexapro), sertraline (Zoloft), duloxetine (Cymbalta), and citalopram (Celexa).Dec 29, 2020
What is the best antidepressant that doesn't cause weight gain?
Antidepressants that do not cause weight gain According to current scientific research, antidepressants that are least likely to cause weight gain are: Effexor (venlafaxine) Wellbutrin (bupropion) Nefazodone (however, this is rarely used because it can cause severe liver problems)Jul 1, 2021
What is a good alternative to Zoloft?
- Lexapro. Zoloft and Lexapro are both SSRIs indicated for the treatment of depression. ...
- Prozac. Prozac is another SSRI medication that works in the same way as Zoloft to increase serotonin activity. ...
- Effexor. ...
- Cymbalta. ...
- Wellbutrin.
Based on their analysis, the review authors concluded sertraline and escitalopram were the best antidepressants overall in terms of efficacy and patient acceptability. Sertraline was found to be more effective than duloxetine by 30%, fluvoxamine (27%), fluoxetine (25%), paroxetine (25%), and reboxetine (85%).Jan 29, 2021