Users of online forums report tianeptine sodium and sulfate begins working within 30-60 minutes when taken orally. However, the onset of effects may be faster when taken via other routes of administration.
How strong is tianeptine?
The standard tianeptine dose is 12.5 mg, three times a day. People do get withdrawal symptoms when they ramp up to hundreds of milligrams to a gram per day and then stop.16 oct 2019
Does tianeptine show up in a drug test?
Drug Monitoring Further, after reaching out to several large national lab testing companies, it does not appear that there are any urine assays, screens, or confirmatory tests that specifically assess for tianeptine use.16 sept 2020
What happens if you take too much tianeptine?
While tianeptine is available by prescription in certain countries, it has a risk of misuse and abuse. Taking high doses of tianeptine can cause drowsiness, confusion, difficulty breathing, coma, and death. Use of tianeptine over a long time can cause withdrawal.
Can tianeptine cause death?
Tianeptine at high doses can be dangerous and can cause an overdose. A 2018 study reports 15 cases of tianeptine overdose, about half being in combination with another substance, 3 of which resulted in death. Another study reported two additional fatal cases of tianeptine overdose in Texas.
How many mg of tianeptine should I take?
Dosing. BY MOUTH: Depression: 25 or 37.5 mg of tianeptine daily has been used as a prescription drug under the guidance of a healthcare professional.
How much tianeptine is an overdose?
Tianeptine overdose fatalities are associated with serum concentrations ranging from 4,000 to 18,000 ng/mL (4). Tianeptine dependence and a withdrawal syndrome of anxiety, sweating, myalgias, chills, and depression have been described (2).13 jul 2018
Can tianeptine get you high?
One case series identified 18 patients taking an average daily dose of tianeptine of 1469 mg/day (~110-fold higher than therapeutic doses) exhibiting marked euphoria and withdrawal, which then precipitated additional drug abuse.16 sept 2020
What are the side effects of tianeptine?
The most common adverse effects are nausea, constipation, abdominal pain, headache, dizziness and changes in dreaming. Anticholinergic effects occur less often with tianeptine than with tricyclic agents. Hepatoxicity is rare.
Is tianeptine bad for your liver?
Side effects A recent review found that it was amongst the antidepressants most prone to causing hepatotoxicity (liver damage), although the evidence to support this concern was of limited quality. Unlike other tricyclic antidepressants, tianeptine does not affect heart function.