bronchodilator in patients with poor response to beta agonists is one of the many uses of magnesium sulfate.
Magnesium is a cofactor in many processes in the body.Lowering the amount of acetylcholine released at the motor end plate is controlled by magnesium sulfate.
The anticonvulsant effect lasts about 30 minutes after it is administered.The start time is 1 hour and the duration of action is 3 to 4 hours.
A prescription for magnesium sulfate can only be obtained from a vet.The Food and Drug Administration does not approve this drug for use in animals, but it is prescribed by veterinarians as an extra-label drug.
It is recommended that magnesium sulfate be used at lower levels in patients with impaired renal function.It is not recommended for patients with a heart block or myocardial damage.
There are side effects of magnesium sulfate.Respiratory paralysis, asystole, and heart block can be caused by overdose.
The normal levels of magnesium in the body are between 1.5 and 3 mEq/L.When magnesium is being used for treatment of convulsions, levels in the range of 4 to 7 mEq/L are considered to be therapeutic.Toxic signs appear at levels of 7 to 10 mEq/L.Narcosis, loss of deep tendon reflexes, and hypotension are some of the symptoms.
Respiratory paralysis, cardiac defects, and ultimately cardiac arrest may result from higher levels.
Monitoring of the serum concentration is indicated when magnesium sulfate is administered.As this may drop, the serum calcium should be monitored.Appropriate fluid replacement therapy should be used to sustain urine output.
Other medications may interact with magnesium sulfate.If your pet is receiving drugs that could interact with magnesium sulfate, it’s a good idea to consult with your vet.Such interactions can include: