The higher the levels of anti-tissue transglutaminase antibodies in your blood, the more likely it is that you have it or a related disorder. Younger children are an exception to this rule. A test may come back negative even if the child has celiac disease.
What is a normal transglutaminase level?
Optimal Result: 0 - 3 U/mL, or 0.00 - 100.00 ug/g. A tissue transglutaminase IgA (tTg-IgA) test is used to help doctors diagnose celiac disease or to see how well people with the condition are doing.
What does a positive IgA test mean?
Tissue Transglutaminase Antibodies (tTG-IgA) the tTG-IgA test will be positive in about 98% of patients with celiac disease who are on a gluten-containing diet. The test's sensitivity measures how correctly it identifies those with the disease.
What does it mean if tTG has been identified?
A tTG blood test detects antibodies to aid in the diagnosis of gluten-sensitive enteropathygluten-sensitive enteropathyGluten-sensitive enteropathy–associated conditions are comorbidities or complications of gluten-related gastrointestinal distress (that is, gluten-sensitive enteropathy or GSE). GSE has key symptoms typically restricted to the bowel and associated tissues; however, there are a wide variety of associated conditions.https://en.wikipedia.org › wikiGluten-sensitive enteropathy–associated conditions - Wikipedia (GSE), such as celiac disease and dermatitis herpetiformis.
What does a positive celiac panel mean?
When positive this test is considered 90 percent sensitive at accurately diagnosing celiac disease because the presence of these antibodies correlates highly with the immune system attacking and destroying the intestinal lining, known as villous atrophy.
What can cause a positive celiac blood test?
According to various studies, it appears that celiac disease may be associated with antibiotic use; history of gastroenteritis, rotavirus, or Campylobacter infection; proton pump inhibitor use; and birth by elective Cesarean section, among other risk factors.
What is a normal tTG IgA level?
The IgA tTG antibody level was elevated at greater than 250 U/mL (normal level is < 15 U/mL); the IgA tTG antibody measurement had been obtained because constipation can be a symptom of CD and there was a positive family history of CD.