Insulin Glargine is an insulin analogue indicated for once-daily subcutaneous administration in the treatment of Type 1 or Type 2 diabetes mellitus patients who require insulin for the control of hyperglycemia. Insulin Glargine is given subcutaneously once a day. It may be administered at any time during the day.
What are the most common side effects of metformin?
The most common side effects are feeling and being sick, diarrhoea, stomach ache and going off your food. Metformin does not cause weight gain, unlike some other diabetes medicines. Metformin may also be called by the brand names Bolamyn, Diagemet, Glucient, Glucophage and Metabet.
What is the role of metformin?
Metformin lowers your blood sugar levels by improving the way your body handles insulin. It's usually prescribed for diabetes when diet and exercise alone have not been enough to control your blood sugar levels. For women with PCOS, metformin lowers insulin and blood sugar levels, and can also stimulate ovulation.
What does metformin do to the liver?
Metformin prevents the liver from dumping more glucose into the blood. Scientists used to think it worked by telling CRTC2 to cooperate with insulin (in other words, reducing insulin resistance.)Sep 7, 2011
Why zinc is added to insulin?
In addition the zinc ions enhance proinsulin's solubility and render insulin insoluble. Zinc ions also appear to play an important role in the microcrystalline character of the precipitated insulin granule.
Does zinc interfere with insulin?
Zinc is known to play a major role in the stabilization of insulin hexamers and in the pancreatic storage of insulin because it can enhance insulin binding to hepatocyte membranes [28].