CREST syndrome is characterized by: Calcinosis: Calcium skin deposits. Raynaud's phenomenon: A condition in which the blood vessels of the fingers and toes spasm when triggered by factors, such as cold, stress or illness. Cold, painful or numb fingers and toes result, which in severe cases may become gangrenous.
Where does scleroderma usually start?
Nearly everyone who has scleroderma experiences a hardening and tightening of the skin. The first parts of the body to be affected are usually the fingers, hands, feet and face. In some people, the skin thickening can also involve the forearms, upper arms, chest, abdomen, lower legs and thighs.3 days ago
Can CREST syndrome be mild?
There are two types of scleroderma -- localized and systemic -- and CREST is considered a mild form of systemic scleroderma. The prognosis for CREST is usually very good.
What is CREST syndrome associated with?
The symptoms involved in CREST syndrome are associated with the generalized form of the disease Systemic sclerosis (scleroderma). CREST is an acronym for the clinical features that are seen in a patient with this disease.31 May 2020
- Small red spots on the hands, face, and upper trunk develop due to dilated tiny blood vessels.
- Spots may also occur on mucosal surfaces such as the lips and throughout the gastrointestinal tract.
- Spots may bleed.
How serious is CREST syndrome?
CREST syndrome coupled with pulmonary hypertension (elevated blood pressures within the lungs) can lead to heart and respiratory failure. See your doctor for advanced, integrated diagnosis and treatment.
Can you live a normal life with CREST syndrome?
In a large 2003 US study by Mayes et al, the survival rate from time of diagnosis was computed to be 77.9% at 5 years, 55.1% at 10 years, 37.4% at 15 years, and 26.8% at 20 years. The extent of skin involvement is a good predictor of survival in patients with scleroderma.
What is the life expectancy of a person with scleroderma?
People who have localized scleroderma may live an uninterrupted life with only minor symptom experiences and management. On the other hand, those diagnosed with an advanced and systemic version of the disease have a prognosis of anywhere from three to 15 years.
Is scleroderma always fatal?
It is the most fatal of all the rheumatologic diseases. Systemic scleroderma is very unpredictable although most cases can be classified into one of four different general patterns of disease (see Classification).
Can CREST syndrome be cured?
CREST Syndrome, a subcategory of the disease, is rarer still. As a result, it is even more deserving of some time in the spotlight. The more we can raise awareness, the more accurately the condition can be diagnosed. And while it is a chronic disease with no known cure, it can be made more manageable with treatment.6 Aug 2020