Ixazomib is in a class of medications called proteasome inhibitors. It works by helping to kill cancer cells.
Is NINLARO a chemo drug?
Ninlaro is a targeted therapy anticancer drug used to treat multiple myeloma.
How long do you take Ixazomib?
An all-oral regimen you can take at home NINLARO® (ixazomib) is a capsule that you take once a week for 3 weeks of a 4-week cycle.
What is Ixazomib used to treat?
Ixazomib is used in combination with lenalidomide and dexamethasone to treat multiple myeloma (a type of bone marrow cancerbone marrow cancerMultiple myeloma (MM), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies. Often, no symptoms are noticed initially. As it progresses, bone pain, anemia, kidney dysfunction, and infections may occur.https://en.wikipedia.org › wiki › Multiple_myelomaMultiple myeloma - Wikipedia) in patients who have received at least one prior treatment. It interferes with the growth of cancer cells, which are eventually destroyed by the body.Dec 1, 2021
Is ixazomib a biologic?
Ixazomib is a modified peptide boronic acid. It is formulated as a stable citrate ester, ixazomib citrate [25], which rapidly hydrolyzes to the biologically active boronic acid form, ixazomib, under physiological conditions (i.e. upon exposure to aqueous solutions or plasma) [25].
Is ixazomib a chemotherapy drug?
Ixazomib is used to treat multiple myeloma (bone marrow cancerbone marrow cancerMultiple myeloma (MM), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies. Often, no symptoms are noticed initially. As it progresses, bone pain, anemia, kidney dysfunction, and infections may occur.https://en.wikipedia.org › wiki › Multiple_myelomaMultiple myeloma - Wikipedia), in combination chemotherapy with lenalidomide and dexamethasone.
Is ixazomib a proteasome inhibitor?
Ixazomib, as a proteasome inhibitor, inhibits the chymotrypsin-like activity of the β5 subunit of the 20S proteasome. Based on the TOURMALINE-MM1 study, ixazomib was proved by the FDA as the orphan drug in November 2015.Jan 7, 2019
Is ixazomib chemo?
Ixazomib is used to treat multiple myeloma (bone marrow cancerbone marrow cancerMultiple myeloma (MM), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies. Often, no symptoms are noticed initially. As it progresses, bone pain, anemia, kidney dysfunction, and infections may occur.https://en.wikipedia.org › wiki › Multiple_myelomaMultiple myeloma - Wikipedia), in combination chemotherapy with lenalidomide and dexamethasone. This combination is usually given after treatment with at least one other cancer medicine has failed.
How long does it take for ixazomib to work?
In a clinical trial, the median time that patients experienced their first response was about 1 month with the NINLARO regimen (NINLARO+lenalidomide+dexamethasone), compared with about 2 months with the placebo regimen (placebo+lenalidomide+dexamethasone).
What is the brand name for ixazomib?
Ixazomib is the generic name for the trade name drug Ninlaro. In some cases, health care professional may use the trade name Ninlaro when referring to the generic drug name, ixazomib.
What is another name for Ixazomib?
Ixazomib (trade name Ninlaro) is a drug for the treatment of multiple myeloma, a type of white blood cell cancer, in combination with other drugs.